['CO', 'COc1ccc2c(c1)[C@H](CBr)N(S(C)(=O)=O)CC2', 'COc1ccc2c(c1)CCN(S(C)(=O)=O)[C@H]2CBr', 'C[SH](=O)=O', 'COc1cc2c(cc1OC)[C@H](CBr)NCC2']
The Murcko scaffold (minmal number of connected rings) of <smiles></smiles> is c1ccc2c(c1)CCNC2.