['CO', 'Cn1ccs/c1=N/C(=O)/C=C/c1ccccc1OC(F)F', 'OC(F)F', 'COc1cccc(/C=C/C(=O)/N=c2/sccn2C)c1', 'CC(=O)/N=c1/sccn1C', 'COc1cccc(C)c1OC(F)F']
The Murcko scaffold (minmal number of connected rings) of <smiles></smiles> is O=C(/C=C/c1ccccc1)/N=c1\[nH]ccs1.