['Clc1ccc(C2CC2)cc1', 'CC1(C)CN(S(N)(=O)=O)CCO1', 'Clc1ccccc1', 'CC1(C)CN(S(=O)(=O)NC2CC2)CCO1']
The Murcko scaffold (minmal number of connected rings) of <smiles></smiles> is O=S(=O)(N[C@@H]1C[C@H]1c1ccccc1)N1CCOCC1.