['Nc1ccc2c(c1)CCO2', 'O=[SH](=O)c1ccc(F)cc1', 'c1ccc2c(c1)CCO2', 'NS(=O)(=O)c1ccc(F)cc1']
The Murcko scaffold (minmal number of connected rings) of <smiles></smiles> is O=S(=O)(Nc1ccc2c(c1)CCO2)c1ccccc1.