['Cc1cc(C)c(N)c(C)c1', 'Cc1cc([SH](=O)=O)ccc1Cl', 'Cc1cc(C)cc(C)c1', 'Cc1cc(S(N)(=O)=O)ccc1Cl']
The Murcko scaffold (minmal number of connected rings) of <smiles></smiles> is O=S(=O)(Nc1ccccc1)c1ccccc1.