decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC\C(=C(\CC)C1=CC=C(O)C=C1)C1=CC=C(O)C=C1.[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCC(O)=O
wspaced:decrease therapeutic efficacy