decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl.CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=C(C=CC=C2)C#N)C1=O
wspaced:decrease therapeutic efficacy