decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1.OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
wspaced:decrease therapeutic efficacy