decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1C=C[C@@]2(O)C#C.[H]C(=O)C1=CC(O)=C(O)C=C1
wspaced:decrease therapeutic efficacy