decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=C(OC(=O)N(C2=O)C2=CC=CC=N2)C2=CC=CC=C2S1(=O)=O.CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy