decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(NC2=C(C=CC=N2)C(O)=O)C=CC=C1Cl.CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy