decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O.[H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2
wspaced:decrease therapeutic efficacy