decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.O=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
wspaced:decrease therapeutic efficacy