decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC.NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
wspaced:decrease therapeutic efficacy