increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:C\C(O)=C(/C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F.[H][C@@]12C[C@@H](O)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
wspaced:increase risk of adverse effects