decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN(CC1)C1=NC2=CC=CC=C2NC2=C1C=C(C)S2.CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=C(C=CC=C2)C#N)C1=O
wspaced:decrease therapeutic efficacy