decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O.CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
wspaced:decrease therapeutic efficacy