decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O.CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)N[C@H]2CC[C@H](C)CC2)C1=O
wspaced:decrease therapeutic efficacy