decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)C2=C(Cl)C(Cl)=CC=C2)CC1.CCCN[C@H]1CCC2=C(C1)SC(N)=N2
wspaced:decrease therapeutic efficacy