decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(C)(C)NCC(O)C1=NC(CO)=C(O)C=C1.COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(=O)OCC(O)=O
wspaced:decrease therapeutic efficacy