decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H]N([H])CCCCC1N([H])C(=O)C(CC2=CN([H])C3=CC=CC=C23)N([H])C(=O)C(CC2=CC=C(O)C=C2)N([H])C(=O)C(CSSCC(N([H])C(=O)C(N([H])C1=O)C(C)C)C(=O)N([H])C(C(C)O)C(=O)N([H])[H])N([H])C(=O)C(CC1=CC2=CC=CC=C2C=C1)N([H])[H].CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
wspaced:decrease therapeutic efficacy