decrease serum concentration
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N1CCNC(C)C1)C1CC1.OC[C@@H]1CC[C@@H](O1)N1C=NC2=C1NC=NC2=O
wspaced:decrease serum concentration