decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(C)CCCC1(OCC2=C1C=CC(=C2)C#N)C1=CC=C(F)C=C1.N[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O)=O
wspaced:decrease therapeutic efficacy