increase QTc-prolonging
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O.[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3
wspaced:increase QTc-prolonging