decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1)C2=O
wspaced:decrease therapeutic efficacy