decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(C(=O)NC2=CC=CC=N2)=C(O)C2=C(C=CS2)S1(=O)=O.CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O
wspaced:decrease therapeutic efficacy