decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12CC3=C(C(O)=C(O)C=C3)C3=CC=CC(CCN1C)=C23.OC1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)C1=CC=C(Cl)C=C1
wspaced:decrease therapeutic efficacy