decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl.[H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2
wspaced:decrease therapeutic efficacy