decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCC(C)C1(CC=C)C(=O)NC(=O)NC1=O.CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1C=C[C@@]2(O)C#C
wspaced:decrease therapeutic efficacy