decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3.[H][C@]12CC[C@]([H])(C[C@@]([H])(C1)OC(C1=CC=CC=C1)C1=CC=CC=C1)N2C
wspaced:decrease therapeutic efficacy