decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O.N[C@@H](CC(=O)N1CCN2C(C1)=NN=C2C(F)(F)F)CC1=CC(F)=C(F)C=C1F
wspaced:decrease therapeutic efficacy