decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21.CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1
wspaced:decrease therapeutic efficacy