decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=NS(=O)(=O)C2=C(N1)C=CC(Cl)=C2.[H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2
wspaced:decrease therapeutic efficacy