decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12N(C)CC[C@@]1(C)C1=C(C=CC(OC(=O)NC)=C1)N2C.[I-].[I-].[I-].CC[N+](CC)(CC)CCOC1=CC=CC(OCC[N+](CC)(CC)CC)=C1OCC[N+](CC)(CC)CC
wspaced:decrease therapeutic efficacy