decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C\C(O)=O.[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
wspaced:decrease therapeutic efficacy