decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O.NC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC=N1
wspaced:decrease therapeutic efficacy