decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1.[H][C@]12CC[C@]([H])(C[C@@H](C1)OC(=O)C(CO)C1=CC=CC=C1)[N+]2(C)C(C)C
wspaced:decrease therapeutic efficacy