decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(CCCCCCCCCCN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.CCN(CC)CCOC(=O)C1(CCCCC1)C1CCCCC1
wspaced:decrease therapeutic efficacy