decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NC(=N)C1=CC=C(OCCCCCOC2=CC=C(C=C2)C(N)=N)C=C1.[H][C@@](CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1)(CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy