decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC(=C)C(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1.CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy