decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
wspaced:decrease therapeutic efficacy