decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C.OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
wspaced:decrease therapeutic efficacy