decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(C)C(=O)C(C(CCCCCC(O)=O)C2=CC=CC=C2)=C(C)C1=O.CC1CC2=CC=CC=C2N1NC(=O)C1=CC(=C(Cl)C=C1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy