decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1.NC(CO)(CO)CO.CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
wspaced:decrease therapeutic efficacy