decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O.[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O.CC(C)C[C@H](CN)CC(O)=O
wspaced:decrease therapeutic efficacy