decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12CC3=C(C(O)=C(O)C=C3)C3=CC=CC(CCN1C)=C23.COC1=CC2=C(SC3=C(C=CC=C3)N2C[C@H](C)CN(C)C)C=C1
wspaced:decrease therapeutic efficacy