decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].[Ca++].[Ca++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.CC1=C(Cl)C=CC=C1NC1=CC=CC=C1C(O)=O
wspaced:decrease therapeutic efficacy