decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN(CC1)C1=NC2=CC=CC=C2NC2=C1C=C(C)S2.COC1=C(C=C(Cl)C=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
wspaced:decrease therapeutic efficacy