increase atrioventricular blocking
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC3=CNC4=CC=CC(=C34)[C@@]1([H])C[C@@H](CSC)CN2CCC.[H][C@](O)(CNC(C)(C)C)COC1=NSN=C1N1CCOCC1
wspaced:increase atrioventricular blocking