decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)COC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl.CCCC[C@H](C)C[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC\C=C\C(O)=O
wspaced:decrease therapeutic efficacy