decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC(=C)C(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1.OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
wspaced:decrease therapeutic efficacy