decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(C)C(=O)OC1=CC(=CC(OC(=O)N(C)C)=C1)C(O)CNC(C)(C)C.COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(=O)OCC(O)=O
wspaced:decrease therapeutic efficacy