decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CCN(C[C@@H]1C=C)[C@]([H])(C2)[C@@H](O)C1=C2C=C(OC)C=CC2=NC=C1.COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
wspaced:decrease therapeutic efficacy