decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O.[H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@@]([H])(O)C([O-])=O.CC1=CC(=CC(C)=C1CC1=NCCN1)C(C)(C)C
wspaced:decrease therapeutic efficacy