decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC1(CCC(C)C)C(=O)NC(=O)NC1=O.[H][C@@]12CC[C@@](O)(CC#N)[C@@]1(C)CCC1=C3CCC(=O)C=C3CC[C@@]21[H]
wspaced:decrease therapeutic efficacy