decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OCC(O)COC(=O)C1=CC=CC=C1NC1=CC=NC2=C(C=CC=C12)C(F)(F)F.CC1CC2=CC=CC=C2N1NC(=O)C1=CC(=C(Cl)C=C1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy