decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1.CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)N[C@H]2CC[C@H](C)CC2)C1=O
wspaced:decrease therapeutic efficacy