decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)\C=C/C(O)=O.CN1CC2C(C1)C1=C(OC3=CC=CC=C23)C=CC(Cl)=C1.CC1=NC=C(N=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
wspaced:decrease therapeutic efficacy