decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=CC(=NN=C1NCCN1CCOCC1)C1=CC=CC=C1.O=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
wspaced:decrease therapeutic efficacy