increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.NC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
wspaced:increase risk of adverse effects