decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[O-][N+](=O)C1=CC=C(O1)\C=N\N1CC(=O)NC1=O.CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
wspaced:decrease therapeutic efficacy