decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2
wspaced:decrease therapeutic efficacy