increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])CCC2=O.CC1=C(SC=C1)C(=CCCN1CCC[C@H](C1)C(O)=O)C1=C(C)C=CS1
wspaced:increase risk of adverse effects