increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.COC1=C(OC)C=C2C3CC(=O)C(CC(C)C)CN3CCC2=C1
wspaced:increase risk of adverse effects