decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(=O)NC(=O)C(C)(C1=O)C1=CCCCC1.[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O
wspaced:decrease therapeutic efficacy