decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O.OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
wspaced:decrease therapeutic efficacy