decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl.CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O
wspaced:decrease therapeutic efficacy