decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=C(OC(=O)N(C2=O)C2=CC=CC=N2)C2=CC=CC=C2S1(=O)=O.NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F
wspaced:decrease therapeutic efficacy