decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(C)C(=O)OC1=C[N+](C)=CC=C1.[H][C@@]12CC3=CC=C(OC4=C5C(CC[N+](C)(C)[C@]5([H])CC5=CC(OC6=C(OC)C=C(CCN1C)C2=C6)=C(O)C=C5)=CC(OC)=C4O)C=C3
wspaced:decrease therapeutic efficacy