increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.[H][C@@]12CC3=C(C=C(O)C=C3)[C@]3(CCCC[C@@]13O)CCN2CC1CCC1
wspaced:increase risk of adverse effects