decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1.CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
wspaced:decrease therapeutic efficacy