increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC=C(\C=C\C(=O)NC2=CC=CC=C2C(O)=O)C=C1OC.[H][C@@]12C[C@H]3OC4(CCCC4)O[C@@]3(C(=O)COC(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
wspaced:increase risk of adverse effects