decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCN(CCC1=CC=CS1)[C@H]1CCC2=C(O)C=CC=C2C1.OC1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C#N)CC1
wspaced:decrease therapeutic efficacy