decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F.CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy