decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21.CC1=C(SC=C1)C(=CCCN1CCC[C@H](C1)C(O)=O)C1=C(C)C=CS1
wspaced:decrease therapeutic efficacy