decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=CC=C(NC2=C(Cl)C=CC=C2F)C(CC(O)=O)=C1.CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(=C1)C(F)(F)F
wspaced:decrease therapeutic efficacy