decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C.NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
wspaced:decrease therapeutic efficacy