decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.CC(CCC1=CC=C(O)C=C1)NCCC1=CC(O)=C(O)C=C1
wspaced:decrease therapeutic efficacy