decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(OC)C=C2C(=O)C(CC3CCN(CC4=CC=CC=C4)CC3)CC2=C1.CN1CCCC(CC2C3=CC=CC=C3SC3=CC=CC=C23)C1
wspaced:decrease therapeutic efficacy