decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCC(CC1)=C1C2=CC=CC=C2C=CC2=CC=CC=C12.CCC1=NN(CCCN2CCN(CC2)C2=CC(Cl)=CC=C2)C(=O)N1CCOC1=CC=CC=C1
wspaced:decrease therapeutic efficacy