decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O.[O-][N+](=O)C1=CC2=C(NC(=O)CN=C2C2=CC=CC=C2Cl)C=C1
wspaced:decrease therapeutic efficacy