decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCCCCC(=O)N[C@H](CN1CCCC1)[C@H](O)C1=CC=C2OCCOC2=C1.CC\C(=C(/C1=CC=CC=C1)C1=CC=C(OCCN(C)C)C=C1)C1=CC=CC=C1
wspaced:decrease therapeutic efficacy