decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1.NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl
wspaced:decrease therapeutic efficacy