decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC#CC(C)C1(CC=C)C(=O)NC(=O)N(C)C1=O.[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H]
wspaced:decrease therapeutic efficacy