decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN(C\C=C\C#CC(C)(C)C)CC1=CC=CC2=CC=CC=C12.[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])CCC2=O
wspaced:decrease therapeutic efficacy