decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2.CC(CN(C)C)CN1C2=CC=CC=C2SC2=C1C=C(C=C2)C#N
wspaced:decrease therapeutic efficacy