decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C2NC(=O)C3=C(N=CC=C3)N(C3CC3)C2=NC=C1.[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@@]4(C)OO[C@@]13[C@]([H])(O[C@@H](OC(=O)CCC(O)=O)[C@@H]2C)O4
wspaced:decrease therapeutic efficacy