decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1.CC[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1C=C[C@@]2(O)C#C
wspaced:decrease therapeutic efficacy