decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:C[C@@H](CC1=CC(O)=C(O)C=C1)[C@H](C)CC1=CC(O)=C(O)C=C1.[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)C(C)CC#CC)[C@@]1([H])C\C(C2)=C\CCCC(O)=O
wspaced:decrease therapeutic efficacy