decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCNC1=C(OC2=CC=CC=C2)C(=CC(=C1)C(O)=O)S(N)(=O)=O.COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1)C2=O
wspaced:decrease therapeutic efficacy