decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CC1=NN=C2CN=C(C3=CC=CC=C3)C3=C(C=CC(Cl)=C3)N12
wspaced:decrease therapeutic efficacy