decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC.NC(=O)C([C@@H]1CCN(CCC2=CC3=C(OCC3)C=C2)C1)(C1=CC=CC=C1)C1=CC=CC=C1
wspaced:decrease therapeutic efficacy