decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1.CN(CCOC1=CC=C(CC2SC(=O)NC2=O)C=C1)C1=CC=CC=N1
wspaced:decrease therapeutic efficacy