decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C)C(C)=C(\C=C\C(\C)=C\C=C\C(\C)=C\C(O)=O)C(C)=C1.[H]\C(C)=C(/C(=C(\[H])C)/C1=CC=C(O)C=C1)\C1=CC=C(O)C=C1
wspaced:decrease therapeutic efficacy