increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC(C)=NN1C1=NC(C)=CC(OC)=N1.[H][C@@]12C[C@H]3OC(C)(C)O[C@@]3(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)CC[C@]12C
wspaced:increase risk of adverse effects