decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN2C(C1)C1=CC=CC=C1CC1=CC=CC=C21.CNCC(O)C1=CC(OC(=O)C(C)(C)C)=C(OC(=O)C(C)(C)C)C=C1
wspaced:decrease therapeutic efficacy