decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=C(OC(=O)N(C2=O)C2=CC=CC=N2)C2=CC=CC=C2S1(=O)=O.NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1
wspaced:decrease therapeutic efficacy