decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(C(O)=O)C1=CC(=CC=C1)C(=O)C1=CC=CC=C1.NC1=NC(=O)C2=NC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)=CN=C2N1
wspaced:decrease therapeutic efficacy