decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2.NS(=O)(=O)C1=C(Cl)C=C2NCNS(=O)(=O)C2=C1
wspaced:decrease therapeutic efficacy