decrease serum concentration
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CN(C[C@]1([H])[C@H]2N)C1=NC2=C(C=C1F)C(=O)C(=CN2C1=C(F)C=C(F)C=C1)C(O)=O.OC[C@@H]1CC[C@@H](O1)N1C=NC2=C1NC=NC2=O
wspaced:decrease serum concentration