decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(OCCCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C=CC(=C1)C(C)=O.CC(C)[C@H]1CC[C@@H](CC1)C(=O)N[C@H](CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy