decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC[C@H](NC(C)C)[C@H](O)C1=C2C=CC(=O)NC2=C(O)C=C1.COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(=O)OCC(O)=O
wspaced:decrease therapeutic efficacy