decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC1=CC=CC=C1Cl.CC(C)N(CC[C@H](C1=CC=CC=C1)C1=C(O)C=CC(C)=C1)C(C)C
wspaced:decrease therapeutic efficacy