decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1CC2=CC=CC=C2N1NC(=O)C1=CC(=C(Cl)C=C1)S(N)(=O)=O.CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
wspaced:decrease therapeutic efficacy