increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.NS(=O)(=O)CC1=NOC2=CC=CC=C12
wspaced:increase risk of adverse effects