decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3.O=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
wspaced:decrease therapeutic efficacy