increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C.FC(F)(F)C1=CC(=CC=C1)N1CCN(CCN2C(=O)NC3=CC=CC=C23)CC1
wspaced:increase risk of adverse effects