decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC2=C(C)C=CC=C2C)CC1.COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
wspaced:decrease therapeutic efficacy