decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC(=C)C(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1.CC1=NC=C(N=C1)C(=O)NCCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1
wspaced:decrease therapeutic efficacy