decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12.[H][C@]12C[C@@H](CN(CCC)[C@]1([H])CC1=CC=CC(O)=C1C2)NS(=O)(=O)N(CC)CC
wspaced:decrease therapeutic efficacy