decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC.CN1CCN(CC(=O)N2C3=CC=CC=C3C(=O)NC3=C2N=CC=C3)CC1
wspaced:decrease therapeutic efficacy