decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O.OC12CC3CC(C1)CC(C3)(C2)NCC(=O)N1CCC[C@H]1C#N
wspaced:decrease therapeutic efficacy