decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OP(O)(=O)OCN1C(=O)NC(C1=O)(C1=CC=CC=C1)C1=CC=CC=C1.[H][C@@]12CC[C@@](O)(CC#N)[C@@]1(C)CCC1=C3CCC(=O)C=C3CC[C@@]21[H]
wspaced:decrease therapeutic efficacy