increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12CN3C4=C([C@@H](COC(N)=O)[C@@]3(OC)[C@@]1([H])N2)C(=O)C(N)=C(C)C4=O.CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
wspaced:increase risk of adverse effects