decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC[N+](CC)(CCNC(=O)C(=O)NCC[N+](CC)(CC)CC1=CC=CC=C1Cl)CC1=CC=CC=C1Cl.C[N+]1(C)CCC(C1)OC(=O)C(O)(C1CCCC1)C1=CC=CC=C1
wspaced:decrease therapeutic efficacy