decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.OC1N=C(C2=CC=CC=C2Cl)C2=C(NC1=O)C=CC(Cl)=C2
wspaced:decrease therapeutic efficacy