decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.CCOC(=O)NC1=C(N)C=C(NCC2=CC=C(F)C=C2)C=C1
wspaced:decrease therapeutic efficacy