decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)C([O-])=O.NC1=CC(=CNC1=O)C1=CC=NC=C1
wspaced:decrease therapeutic efficacy