decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CCC2=O.CCC(=O)C1(CCN(C)CC1)C1=CC(O)=CC=C1
wspaced:decrease therapeutic efficacy