decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1CCN(CC1)C1=NC2=CC=CC=C2NC2=C1C=C(C)S2.[H][C@@]12C[C@]1([H])N([C@@H](C2)C#N)C(=O)[C@@H](N)C12CC3CC(CC(O)(C3)C1)C2
wspaced:decrease therapeutic efficacy