decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1.CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy