increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1.C\C(O)=C(/C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F
wspaced:increase risk of adverse effects