decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1.N[C@@H](CC(=O)N1CCN2C(C1)=NN=C2C(F)(F)F)CC1=CC(F)=C(F)C=C1F
wspaced:decrease therapeutic efficacy