decrease serum concentration
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC(CC2=CN=C(N)N=C2N)=CC(OC)=C1OC.CC(C)OC(=O)[C@H](C)N[P@](=O)(OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@](C)(F)[C@@H]1O)OC1=CC=CC=C1
wspaced:decrease serum concentration