increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C=C(C=C1)C1=CC2=C(C=C1)C=C(C=C2)C(O)=O)C12CC3CC(CC(C3)C1)C2.OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O
wspaced:increase risk of adverse effects