decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12N(C)CC[C@@]1(C)C1=C(C=CC(OC(=O)NC)=C1)N2C.O=C(O[C@H]1CN2CCC1CC2)N1CCC2=CC=CC=C2[C@@H]1C1=CC=CC=C1
wspaced:decrease therapeutic efficacy