decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCC(C)C1(CC)C(=O)NC(=S)NC1=O.[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(C=C3CC[C@@]21[H])=NO
wspaced:decrease therapeutic efficacy