decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12C[C@@H](CN(CCC)[C@]1([H])CC1=CC=CC(O)=C1C2)NS(=O)(=O)N(CC)CC.CCN1CCCC1CNC(=O)C1=C(OC)C=CC(=C1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy