decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCNC(C)C(=O)NC1=C(SC=C1C)C(=O)OC.CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
wspaced:decrease therapeutic efficacy