decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(C1CCCCN1)C1=CC(=NC2=C1C=CC=C2C(F)(F)F)C(F)(F)F.CN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1
wspaced:decrease therapeutic efficacy