decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NS(=O)(=O)C1=C(Cl)C=C2NC(NS(=O)(=O)C2=C1)C(Cl)Cl.COC1=CC2=C(C=C1)C(C)(C)C(=O)N(CCC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1)C2=O
wspaced:decrease therapeutic efficacy