decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=CC=C(C=C1)C1=CC(=NN1C1=CC=C(C=C1)S(N)(=O)=O)C(F)(F)F.CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy