increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC(NCC2=C(C)C3=C(C=C2)N=C(N)N=C3N)=CC(OC)=C1OC.COC(=O)C1=C(NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC(C)C)C#N
wspaced:increase risk of adverse effects