decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=C(C=C(Cl)C=C2)N(C2=CC=CC=C2)C(=O)CC1=O.COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
wspaced:decrease therapeutic efficacy