decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@](CC)(NC1=NC=NC2=C1N=CN2)C1=NC2=CC=CC(F)=C2C(=O)N1C1=CC=CC=C1.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1
wspaced:decrease therapeutic efficacy