decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)COC(=O)CC1=CC=CC=C1NC1=C(Cl)C=CC=C1Cl.NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F
wspaced:decrease therapeutic efficacy