increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CCCN1C(=O)[C@H](CC1=CC=CC=C1)N1C(=O)[C@](C)(NC(=O)[C@H]3CN(C)[C@]4([H])CC5=CNC6=CC=CC(=C56)C4=C3)O[C@@]21O.CC[C@H]1[C@@H](CC2=CN=CN2C)COC1=O
wspaced:increase risk of adverse effects