increase nephrotoxic
prompt:molecule-molecule interaction [SEP] smiles:CN(C(C)=O)C1=C(I)C(C(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO)=C(I)C(NC(C)=O)=C1I.[H][N]([H])([H])[Pt](Cl)(Cl)[N]([H])([H])[H]
wspaced:increase nephrotoxic