decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(CCl)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O.CCC1=C(C)CN(C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)N[C@H]2CC[C@H](C)CC2)C1=O
wspaced:decrease therapeutic efficacy