decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1.NS(=O)(=O)C1=C(Cl)C=CC(=C1)C1(O)NC(=O)C2=CC=CC=C12
wspaced:decrease therapeutic efficacy