decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(C)C(NC2=CC=CC=C2C(O)=O)=CC=C1.CC1CC2=CC=CC=C2N1NC(=O)C1=CC(=C(Cl)C=C1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy