decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:ClC1=CC2=C(OC3=CC=CC=C3N=C2N2CCNCC2)C=C1.[H][C@@]12C[C@@H](C)[C@](O)(C(=O)CCl)[C@@]1(C)C[C@H](O)[C@@]1(Cl)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
wspaced:decrease therapeutic efficacy