decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NC(=O)N1C2=CC=CC=C2C=CC2=CC=CC=C12.[H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=CC=C(OC(=O)N(CCCl)CCCl)C=C3CC[C@@]21[H]
wspaced:decrease therapeutic efficacy