decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(C\C=C(/C)CCC(=O)OCCN2CCOCC2)C(O)=C2C(=O)OCC2=C1C.[H][C@@]12CC(=O)[C@H](CCCCCCC(O)=O)[C@@]1([H])CC[C@@](O)(O2)C(F)(F)CCCC
wspaced:decrease therapeutic efficacy