decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NCCN.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CN1C2=C(NC=N2)C(=O)N(C)C1=O.CNC1=NC2=C(C=C(Cl)C=C2)C(C2=CC=CC=C2)=[N+]([O-])C1
wspaced:decrease therapeutic efficacy