decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12N(C)CC[C@@]1(C)C1=C(C=CC(OC(=O)NC)=C1)N2C.CN1CCN(CC(=O)N2C3=CC=CC=C3C(=O)NC3=C2N=CC=C3)CC1
wspaced:decrease therapeutic efficacy