decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(OC)C(CS(=O)C2=NC3=C(N2)C=C(OC(F)F)C=C3)=NC=C1.OP(O)(=O)C(SC1=CC=C(Cl)C=C1)P(O)(O)=O
wspaced:decrease therapeutic efficacy