decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1
wspaced:decrease therapeutic efficacy