decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(CCN2CCC(CC2)C2=NOC3=C2C=CC(F)=C3)C(=O)N2CCCC(O)C2=N1.CCC1=CN=C(CCOC2=CC=C(CC3SC(=O)NC3=O)C=C2)C=C1
wspaced:decrease therapeutic efficacy