decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(=O)OCOC(=O)C(C)(C)C.COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
wspaced:decrease therapeutic efficacy