decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[Ca++].[Ca++].[Ca++].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.OC(CC([O-])=O)(CC([O-])=O)C([O-])=O.CC(CCC1=CC=C(O)C=C1)NCCC1=CC(O)=C(O)C=C1
wspaced:decrease therapeutic efficacy