decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12N(C)CC[C@@]1(C)C1=C(C=CC(OC(=O)NC)=C1)N2C.ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1
wspaced:decrease therapeutic efficacy