decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N3CCNC(C)C3)C(F)=C12.OS(=O)(=O)OC1=CC=C(C=C1)C(C1=CC=C(OS(O)(=O)=O)C=C1)C1=CC=CC=N1
wspaced:decrease therapeutic efficacy