decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CNCC1=CC=C(C=C1)C1=C2CCNC(=O)C3=C2C(N1)=CC(F)=C3.COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C
wspaced:decrease therapeutic efficacy