increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=NC(N)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O.CC1=C(C=NO1)C(=O)NC1=CC=C(C=C1)C(F)(F)F
wspaced:increase risk of adverse effects