decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O.CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=C(C=CC=C2)C#N)C1=O
wspaced:decrease therapeutic efficacy