decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H]C(=N[C@@H]1C(=O)N2[C@@H](C(=O)OCOC(=O)C(C)(C)C)C(C)(C)S[C@]12[H])N1CCCCCC1.COC1=C(C\C=C(/C)CCC(O)=O)C(O)=C2C(=O)OCC2=C1C
wspaced:decrease therapeutic efficacy