decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(C(=O)NC2=NC=C(C)S2)=C(O)C2=C(C=CC=C2)S1(=O)=O.NS(=O)(=O)C1=CC2=C(NCNS2(=O)=O)C=C1C(F)(F)F
wspaced:decrease therapeutic efficacy