decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(NC(C)(C)C)C(=O)C1=CC(Cl)=CC=C1.[H][C@@]12OC3=C(OC)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])CCC2=O
wspaced:decrease therapeutic efficacy