decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O.[H][C@@](CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1)(CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy