decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C2=CC=CC=C2C(NCCCCCCC(O)=O)C2=C(C=C(Cl)C=C2)S1(=O)=O.COC1=NC(C)=NC(Cl)=C1NC1=NCCN1
wspaced:decrease therapeutic efficacy