decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@@](O)(CC=C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H].OC1=C(CC2=C(O)C3=C(OC2=O)C=CC=C3)C(=O)OC2=C1C=CC=C2
wspaced:decrease therapeutic efficacy