decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCN(C)CC2)C=C1.N[C@@H](CC1=CC(O)=C(O)C=C1)C(O)=O
wspaced:decrease therapeutic efficacy