decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl.[H][C@@](CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1)(CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy