decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O.CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1
wspaced:decrease therapeutic efficacy