decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:NS(=O)(=O)C1=C(Cl)C=C2NC=NS(=O)(=O)C2=C1.CN1C(=O)C=C(N2CCC[C@@H](N)C2)N(CC2=C(C=CC=C2)C#N)C1=O
wspaced:decrease therapeutic efficacy