decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCC(=C)C(=O)C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1.[H][C@@](CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1)(CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy