increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC2=C(C=C1)C=C(CCC(C)=O)C=C2.[H][C@@]12CC(=C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
wspaced:increase risk of adverse effects