decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O.CCOC1=C(C=CC(CC(=O)N[C@@H](CC(C)C)C2=CC=CC=C2N2CCCCC2)=C1)C(O)=O
wspaced:decrease therapeutic efficacy