decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3.ClC1=CC2=C(C=C1)C(=C1CCNCC1)C1=C(CC2)C=CC=N1
wspaced:decrease therapeutic efficacy