decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(C)NC(=O)NS(=O)(=O)C1=C(NC2=CC=CC(C)=C2)C=CN=C1.[H][C@@](CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1)(CC1=CC=CC=C1)C(O)=O
wspaced:decrease therapeutic efficacy