decrease excretion rate
prompt:molecule-molecule interaction [SEP] smiles:CCN[C@@H]1C[C@H](N)[C@@H](O[C@H]2OC(CN)=CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1OC[C@](C)(O)[C@H](NC)[C@H]1O.NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1
wspaced:decrease excretion rate