decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@@](O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H].CCCNC(=O)NS(=O)(=O)C1=CC=C(Cl)C=C1
wspaced:decrease therapeutic efficacy