decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:C[C@@H](C1=NC=NC=C1F)[C@](O)(CN1C=NC=N1)C1=C(F)C=C(F)C=C1.CC(=O)OC1=CC2=C(CCN(C2)C(C(=O)C2CC2)C2=CC=CC=C2F)S1
wspaced:decrease therapeutic efficacy