decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:COCCCOC1=C(C)C(CS(=O)C2=NC3=CC=CC=C3N2)=NC=C1.[H][C@@](N1CCC2=C(C1)C=CS2)(C(=O)OC)C1=CC=CC=C1Cl
wspaced:decrease therapeutic efficacy