decrease analgesic
prompt:molecule-molecule interaction [SEP] smiles:COC1=CC=CC(=C1)[C@@]1(O)CCCC[C@@H]1CN(C)C.[H][C@@]1(C[C@@]2([H])C[C@]3([H])C[C@@]([H])(C1)N2CC3=O)OC(=O)C1=CNC2=C1C=CC=C2
wspaced:decrease analgesic