decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCN(CC)C(=O)C(=C\C1=CC(=C(O)C(O)=C1)[N+]([O-])=O)\C#N.NC(=O)C1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)N1CCCCC1
wspaced:decrease therapeutic efficacy