decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=C(NC2=C(C=CC=N2)C(O)=O)C=CC=C1Cl.CC1NC2=CC(Cl)=C(C=C2C(=O)N1C1=CC=CC=C1C)S(N)(=O)=O
wspaced:decrease therapeutic efficacy