decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@]12C[C@@H](O)C=C[C@]11CCN(C)CC3=C1C(O2)=C(OC)C=C3.OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2
wspaced:decrease therapeutic efficacy