decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC.OC(C1=CC=CC=C1)(C1=CC=CC=C1)C12CC[N+](CCOCC3=CC=CC=C3)(CC1)CC2
wspaced:decrease therapeutic efficacy