decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC(=C)[C@]1([H])[C@@]3([H])CCCC=C3CC[C@@]21[H].OC(=O)CC(O)(CC(O)=O)C(O)=O
wspaced:decrease therapeutic efficacy