decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1.CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy