increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.[H][C@@]12CC3=CC=C(O)C=C3[C@@](C)(CCCCC1)[C@H]2N
wspaced:increase risk of adverse effects