increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=C2O[C@H]3C(=O)CC[C@@]4(O)[C@H]5CC(C=C1)=C2[C@@]34CCN5C.CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O
wspaced:increase risk of adverse effects