increase central nervous system depressant
prompt:molecule-molecule interaction [SEP] smiles:CO[C@]12CC[C@@]3(C[C@@H]1[C@](C)(O)C(C)(C)C)[C@H]1CC4=C5C(O[C@@H]2[C@@]35CCN1CC1CC1)=C(O)C=C4.CCN1CCC[C@H]1CNC(=O)C1=C(OC)C=CC(Br)=C1OC
wspaced:increase central nervous system depressant