decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CN1C(C(=O)NC2=NC=CC=C2)=C(O)C2=C(C=CC=C2)S1(=O)=O.CCC1NC(=O)C2=CC(=C(Cl)C=C2N1)S(N)(=O)=O
wspaced:decrease therapeutic efficacy