decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(C)CC[C@]1([H])[C@@]3([H])CC[C@H](OC(C)=O)C=C3CC[C@@]21[H].NC(=N)NC(=N)NCCC1=CC=CC=C1
wspaced:decrease therapeutic efficacy