decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2.[H][C@@](N1CCC2=C(C1)C=CS2)(C(=O)OC)C1=CC=CC=C1Cl
wspaced:decrease therapeutic efficacy