decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:[H][C@@]12CC[C@@](OC(C)=O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CC\C(C=C3CC[C@@]21[H])=N/O.OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
wspaced:decrease therapeutic efficacy