decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:OC1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C#N)CC1.[H][C@]12C[C@@H](CN(CCC)[C@]1([H])CC1=CC=CC(O)=C1C2)NS(=O)(=O)N(CC)CC
wspaced:decrease therapeutic efficacy