increase risk of adverse effects
prompt:molecule-molecule interaction [SEP] smiles:COC1=NC(N)=NC2=C1N=CN2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O.CN1CCN(CC1)C1=NC2=CC(Cl)=CC=C2NC2=CC=CC=C12
wspaced:increase risk of adverse effects