increase atrioventricular blocking
prompt:molecule-molecule interaction [SEP] smiles:COC1=C(OC)C=C2[C@@H](CN(C)CCCN3CCC4=CC(OC)=C(OC)C=C4CC3=O)CC2=C1.COC[C@@H](NC(C)=O)C(=O)NCC1=CC=CC=C1
wspaced:increase atrioventricular blocking