decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:O=C1NC2=CC(OCCCCN3CCN(CC3)C3=C4C=CSC4=CC=C3)=CC=C2C=C1.CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
wspaced:decrease therapeutic efficacy