decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC1=NC=C(C=C1)C1=C(C=C(Cl)C=N1)C1=CC=C(C=C1)S(C)(=O)=O.CN1C(CSCC(F)(F)F)NC2=CC(Cl)=C(C=C2S1(=O)=O)S(N)(=O)=O
wspaced:decrease therapeutic efficacy