decrease therapeutic efficacy
prompt:molecule-molecule interaction [SEP] smiles:CC(C)(C)C1=NC(=C(S1)C1=NC(N)=NC=C1)C1=C(F)C(NS(=O)(=O)C2=C(F)C=CC=C2F)=CC=C1.CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO
wspaced:decrease therapeutic efficacy